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Polkadot Flagship Conference sub0 SYMBIOSIS Returns November 14–16 in Argentina

Polkadot’s sub0 SYMBIOSIS hits Buenos Aires Nov 14–16: 3 days of code, culture & Web3 innovation

By Jonathan DuranSeptember 2, 2025

Three days of code, culture, and collaboration to shape the future of decentralized systems

Buenos Aires, Argentina – WebZero and Polkadot announce sub0 SYMBIOSIS, the ultimate Polkadot flagship conference, happening November 14–16, 2025, in the heart of Buenos Aires. The event will bring together builders, innovators, and global Web3 leaders for three days of cutting-edge discussions, hands-on workshops, a 24-hour hackathon, and the industry’s best after-hours gatherings.

Bubble Studio, a 3,000m² brutalist creative playground loved by brands like Nike, Netflix, and Pepsi has been secured as the main hub of action - with its raw aesthetic, swimming pool, dance floors, and multiple stages, it’s the perfect backdrop for an event that’s as ambitious as the tech it celebrates.

Seun Lanlege, Co-Founder & CEO of Hyperbridge shared, "Sub0 in Buenos Aires in November is the perfect stage to announce the next phase for Hyperbridge: the first verifiable multichain bridge. We look forward to hosting an activation at the flagship conference to show Hyperbridge's permissionless, incentivized relayer and deflationary token model, designed to build a secure and healthy ecosystem for the future of Web3.”

This year’s theme, “Symbiosis,” signals a defining moment for Polkadot and the Web3 space. In an era of global volatility, economic meltdowns, broken trust in institutions, and information gatekeeping, Polkadot is doubling down on building resilient, censorship-resistant, privacy-first infrastructure for an unstable world. Expect deep dives into the ecosystem’s most powerful tools, from Polkadot Hub and the Polkadot SDK, to the groundbreaking JAM Protocol. Attendees will get the alpha on all the latest initiatives that will shape the next generation of decentralized systems.

sub0 SYMBIOSIS is designed for builders, founders, investors, students, and Web3 thought leaders. A scholarship program will bring top talent from leading universities in Buenos Aires, while local voices and LATAM-based financial innovators will join the stage alongside Polkadot’s core visionaries. Past editions featured Dr. Gavin Wood, Shawn Tabrizi, and Robert Habermeier, and this year promises even more. The first wave of headliners drops September 15.

With Devconnect taking place in Argentina the same week, sub0 SYMBIOSIS is perfectly positioned to capture global Web3 attention and showcase how Polkadot’s tech can tackle real-world challenges in regions like Latin America, where economic instability highlights the urgent need for open, decentralized systems.

Beyond the main event, sub0 SYMBIOSIS is set to deliver an atmosphere unlike any other Web3 conference. Over 25 side events will keep the vibe electric across three days, blending serious networking with unforgettable cultural experiences. Content from both stages will be livestreamed on sub0.gg, hosted by Brooke Lacey and Evan Mann, giving anyone unable to attend in person access to all the keynotes, panels, and product reveals as they happen. The Kusamarian will also be on hand to deliver a steady stream of community-based reporting and updates throughout the conference.

Attendees can dive into two hackathons, including the Polkadot Hack and Web3 Marketing Hack with $15,000 in bounties, and a 24-hour hackerspace with round-the-clock access. Between code sprints, guests can recharge at the Hydration rooftop beach, explore the gaming center featuring Mythical Games’ most popular titles, or join immersive learning sessions with the Polkadot Blockchain Academy. Yet the vibes don’t end there: live DJs, great drinks, and a private chef set the bar high for an environment where creativity, culture, fun, and technology converge in a true symbiosis. If you’ve ever wanted to experience what a future-proof internet feels like, this is your chance.

Confirmed community partners:
NerdConf, DOTLatam, Fundación Blockchain Argentina, Seed Latam, Cripto LaPlata, La Multisig, Mujeres en Bitcoin, La Blocka, CriptoUNAM, Frutero Club, Undercode, Solow, Super Pioneros, Chipped & H.ER DAO.

Conference Highlights

  • Developer Sessions & Workshops: Deep dives into Polkadot’s stack and the future of Web3
  • Hackathons: Two major competitions, including a 24-hour build sprint with $20,000 in bounties
  • Showcases & Product Launches: Reveals for cutting-edge tools and applications
  • Gaming & Culture: Mythical Games, rooftop lounges, music, and immersive art
  • Networking & Community: 25+ curated side events designed to spark collaboration

Key Details


About WebZero
WebZero is a global event and DevRel force presenting sub symbiosis, the leading flagship conference for the Polkadot ecosystem from November 14-16, 2024, in Beunos Aires, Argentina.

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